Oxidative Stress In Anti Thyroperoxidase Antibody Positive Hypothyroid Patients

Study of oxidative stress and lipid profile in hypothyroid patients

The incidence of hypothyroidism in India is high and it is not adequately controlled. The pathogenesis of hypothyroidism is not very clear, however increased oxidative stress have been reported. Pathological consequences of hypothyroidism point to a high potential for antioxidant imbalance. The present study was carried out to evaluate oxidative stress (MDA, Vitamin C) and to correlate these pa...

Oxidative stress in hypothyroid patients and the role of antioxidant supplementation

CONTEXT The available data concerning oxidant stress and antioxidant capacity in hypothyroidism are scanty and inconclusive. While some authors suggest that tissues may be protected from oxidant damage because of a hypometabolic state in hypothyroidism, others report increased oxidative stress in hypothyroidism. Selenium acts as a cofactor for the thyroid hormone (TH) deiodinases that activate ...

An evaluation of stress oxidative and serum electrolytes in female hypothyroid patients

Prevalence of positive anti-neutrophil cytoplasmic antibody (ANCA) in patients receiving anti-thyroid medication.

OBJECTIVE Vasculitis is a rare complication of anti-thyroid medications. There are 32 cases of anti-neutrophil cytoplasmic antibody (ANCA)-positive vasculitis in association with anti-thyroid medication reported in the English literature. The objectives of this study were to assess the frequency of positive ANCA in patients on long-term anti-thyroid medication, and to follow patients prospectiv...

Reduction of oxidative stress marker levels by anti-TNF-alpha antibody, infliximab, in patients with rheumatoid arthritis.

OBJECTIVE The aim of this study was to evaluate the effects of anti-TNF-alpha antibody, infliximab, on oxidative stress markers representing DNA damage, lipid peroxidation, and glycoxidation. METHODS Twenty-three RA patients underwent infliximab treatment and were analyzed for 30 weeks. Six patients who experienced side effects and one patient who had a reduced efficacy of infliximab were dis...